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Featured Articles
Psychedelics in Psychiatry: Psilocybin for Treatment-Resistant Depression
A critical clinical and neurobiological analysis of psilocybin-assisted therapy for treatment-resistant depression, examining 5-HT2A receptor pharmacology, TrkB/mTOR-mediated neuroplasticity, Default Mode Network modulation, Phase 2b and Phase 3 COMP360 trial outcomes, methodological challenges of functional unblinding, and the evolving regulatory landscape.
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Pretraining, Continual Training, SFT, DPO, and Alignment Methods for Large Language Models
A comprehensive technical survey of the modern Large Language Model (LLM) training pipeline, covering autoregressive pretraining, continual domain-adaptive pretraining (CPT), supervised fine-tuning (SFT), parameter-efficient adaptation (LoRA, QLoRA), and preference alignment algorithms (RLHF, DPO, IPO, KTO, ORPO, SPIN, RLAIF) with their mathematical objectives and engineering trade-offs.
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How EU Law Reshapes National Legal Orders and Affects Citizens
A critical legal analysis of the structural mechanisms through which European Union law reshapes national legal orders and affects citizens, examining supremacy, direct effect, state liability, and Article 267 TFEU alongside the democratic deficit, subsidiarity failures, judicial activism, and constitutional identity conflicts with national supreme courts.
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Latest Articles
Psychedelics in Psychiatry: Psilocybin for Treatment-Resistant Depression
Pretraining, Continual Training, SFT, DPO, and Alignment Methods for Large Language Models
How EU Law Reshapes National Legal Orders and Affects Citizens
Brain-Computer Interfaces and Neuralink: Where the Clinical Evidence Actually Stands
Agent Plugins v1.0 and the Illusion of Portability
